Connectomes.org is a website describing current efforts to comprehensively map out mammalian whole-brain connectivity and structure at the synaptic-level using high-throughput volume electron microscopy. |
Project Leader: Shawn Mikula, PhD
Whole Mouse Brain Volume Electron Microscopy
Max Planck Institute for Neurobiology
Shawn Mikula is a neuroscientist devoted to comprehensively mapping mammalian whole-brain connectivity and structure.
He completed his Ph.D. in neuroscience at the Johns Hopkins University School of Medicine at the Krieger Mind-Brain Institute in Baltimore, MD. He subsequently worked with Ted Jones at the University of California (Davis) to develop the BrainMaps project, an interactive multiresolution next-generation brain atlas for various mammalian species. During subsequent post-doctoral work with Winfried Denk at the Max Planck Institute for Medical Research in Heidelberg, Germany, he developed methods to prepare small mammalian brains and image them using high-throughput volume electron microscopy. He is currently working on ultrastructurally mapping the whole mouse brain at single synapse resolution. Longer term, his goal is to use high-throughput electron microscopy to map the whole-brain circuitry of small non-human primates.