Project Leader: Shawn Mikula, PhD
Whole Mouse Brain Volume Electron Microscopy
Max Planck Institute
Shawn Mikula is a neuroscientist devoted to comprehensively mapping mammalian whole-brain connectivity and structure. Shawn completed his Ph.D. in neuroscience at the Johns Hopkins University School of Medicine at the Krieger Mind-Brain Institute in Baltimore, MD. He subsequently worked with Ted Jones at the University of California (Davis) as the architect of the BrainMaps project, an interactive multiresolution next-generation brain atlas for various mammalian species. During subsequent post-doctoral work with Winfried Denk at the Max Planck Institute for Medical Research in Heidelberg, Germany, he developed new methods for staining and high-throughput imaging of whole mouse brains using serial blockface electron microscopy, and he is currently working on ultrastructurally mapping the whole mouse brain at single synapse resolution. Longer term, he aims to scale his methods to comprehensively map larger brains, including primates.